Mon/Wed/Fri 10:00 am-10:50 am
Hutchison 420
Prof.
Patrick Holland
Hutchison 126
Phone 3-3092
Office hours by appointment
CHM 414 is switching over to BlackBoard!! Please go to
http://my.rochester.edu/
Learning Objectives:
Assignments:
Readings and Discussion Questions
Problem Set 1
Problem Set 2 requires VMD and the following files: ah1.pdb and ah2.pdb
Proposal
Presentation Assignments
Take-Home Midterm Exam
Take-Home Final Exam
Inorganic
chemistry
resources:
Hard and Soft Acids and Bases
Webelements
More on Crystal
Field Theory
Awesome Clickable d Orbitals
Less Awesome, but Printable d Orbitals
Kinetics
Handout
Biomolecule
visualization
resources:
Visual Molecular Dynamics (VMD): needed for Problem Set 2
Alternatives:
Protein Explorer: Site 1 Site 2 Download
CHIME (necessary for Protein Explorer)
SwissPDB Viewer: Download
RasMol: Download
PyMol: Download
Proteomics resources:
Protein Data
Bank
Genbank
(sequence, sequence similarity searches)
BLAST
(click Protein-protein BLAST to find proteins with sequence similarity)
BLAST
tutorial
CLUSTAL (visualizing multiple alignments)
EXPASY (proteomics links and resources)
PROMISE (metalloenzyme database; out of date)
PIR Protein Sequence Database
Other links of potential interest:
Valinomycin
structure (requires Chime)
Gramicidin
structure (requires Chime)
Ion Channel Web Links
Potassium
channel
Zinc
finger-DNA
complex
Biological
transport agents
View of human
transferrin N-terminal domain
View of
bullfrog
M ferritin
Oxygen
binding to metalloproteins
Structure
of photosynthetic reaction center
Structure of Photosystem II
Structure of particulate methane monooxygenase
Information
on cellular respiration
Journals (available through
U
of R):
Chemical
Reviews (February 2004 issue on biomimetic inorganic chemistry)
PNAS
(April 2003 issue on bioinorganic chemistry)
Chemical
Reviews (April 2002 issue on nitric oxide chemistry)
Chemical
Reviews (November 1996 issue on bioinorganic enzymology)
Chemical
Reviews (September 1999 issue on medicinal inorganic chemistry)
Current
Opinion in Chemical Biology (April 2000 issue on bioinorganic
chemistry)
Current
Opinion in Chemical Biology (April 2004 issue on bioinorganic
chemistry)
Journal
of Biological Inorganic Chemistry (JBIC)
Inorganic
Chemistry
Journal
of Inorganic Biochemistry
Current
Opinion on Chemical Biology
Bioinorganic Chemistry Research at Rochester:
Bren group