Course
Syllabus |
||
Lecture |
Topic |
Reading |
Sept.
3 |
Scope
of organic chemistry |
|
5 |
The
classical structural model |
Chap.
1.1-1.2, 1.9 |
8 |
The
orbital model |
Chap.
1.3-1.4, 1.6-1.7 |
10 |
The
hybridization model |
Chap.
1.8 |
12 |
Isoelectronic
analogies; resonance |
Chap.
1.5 |
15 |
Acids
& bases; functional groups |
Chap.
2.2-2.5 |
17 |
Conformational
analysis |
Chap.
2.6-2.8 |
19 |
Conformations
of rings, ring strain |
Chap.
4.1-4.2 |
22 |
Cyclohexane
conformations |
Chap.
4.3-4.7 |
24 |
Thermodynamics
and kinetics |
Chap.
2.1 |
26 |
Thermokinetic
principles; Observations on alkane halogenation |
|
29 |
Chlorination
of alkanes; selectivity |
Chap.
3.1-3.4 |
Oct.
1 |
Structure
of free radicals; Review |
Chap.
3.5-3.8, 3.10 |
2 |
Prelim
1 |
|
3 |
Resonance
model |
Chap.
14.1-14.2; 22.1 |
8 |
Chirality
|
Chap.
5.1-5.4 |
10 |
Symmetry
|
Chap.
5.5-5.6 |
13 |
Further
symmetry considerations |
Chap.
5.7-5.8 |
15 |
Cycloalkane
conformations and chirality |
|
17 |
Nucleophilic
substitutions (SN2) |
Chap.
6.1-6.6 |
20 |
Nucleophilic
substitutions (SN2) |
Chap.
6.7-6.9 |
22 |
SN1
nucleophilic substitutions |
Chap.
7.1-7.5 |
24 |
SN1
nucleophilic substitutions |
|
27 |
E2
eliminations |
Chap.
7.6-7.9 |
29 |
Alcohols:
properties & synthesis |
Chap.
8.1-8.5 |
31 |
Oxidation;
Grignard reagents; |
Chap.
8.6-8.8 |
Nov.
3 |
Synthesis
|
Chap.
8.9 |
5 |
Substitution
reactions with alcohols; carbocation rearrangements |
Chap.
9.1-9.3 |
6 |
Prelim
2 |
|
7 |
Ether
synthesis and reactions |
Chap.
9.4-9.8 |
10 |
Oxacyclopropanes
(Epoxides) |
Chap.
9.9-9.10 |
12 |
Alkenes:
Addition of H-X |
Chap.
11.1-11.3, 11.9-11.11 |
Chap.
12.1, 12.3-12.4 |
||
14 |
Bromination
and Related Additions |
Chap.
12.5-12.6 |
17 |
Oxymercuration
and Hydroboration |
Chap.
12.7-12.8 |
19 |
Cyclopropanation
and Epoxidation |
Chap.
12.9-12.10 |
21 |
Hydrogenation,
KMnO4, OsO4, Ozonolysis |
Chap.
12.2, 12.11-12.12 |
24 |
The
HBr Problem |
Chap.
12.13 |
26 |
Special
Topics |
|
Dec.
1 |
Synthesis |
|
3 |
Review |
|
4 |
Prelim
3 |
|
5 |
Electrophilic
additions to alkynes |
Chap.
13.1-13.3, 13.7-13.8 |
8 |
Alkynes:
synthesis |
Chap.
13.4-13.6 |
10 |
Review |
|
15 |
Final
Exam |